The aim of the present study was to evaluate the hydro-alcoholic extract of Portulaca oleracea L. leaf against ethanol-induced hepatic damage. Ethanol feeding resulted in liver injury as indicated by the serum activities of marker enzymes such as AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), TB (total bilirubin) and TG (triglyceride). Post treatment of Portulaca oleracea L. extract reversed these alterations to near normal. The result of this study confirms the regenerative changes in liver by action of Portulaca oleracea L.
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